Compute the stoichiometry of interaction using the method described in ...

Source: R/Main_functions.R

Compute the stoichiometry of interaction using the method described in ...

row_stoichio(df, idx_group_1, idx_group_2, idx_bait, Npep, log = TRUE,
  substract_ctrl = TRUE, use_mean_for_bait = TRUE, idx_group_1_mean,
  idx_group_2_mean)

Arguments

df

a data frame
idx_group_1

column indexes corresponding to the first group (bait background)
idx_group_2

column indexes corresponding to the second group (ctrl background)
idx_bait

row index for the bait protein
Npep

numeric vector containing the number of theoretically observable peptides for each protein
log

logical, use the geometric mean instead of the arithmetic mean
substract_ctrl

logical, substract ctrl intensities in the calculation of stoichiometries
use_mean_for_bait

logical, average bait intensities across all conditions to compute interaction stoichiometries
idx_group_1_mean

if use_mean_for_bait is TRUE, column indexes for the bait protein corresponding to the first group (bait background)
idx_group_2_mean

if use_mean_for_bait is TRUE, column indexes for the bait protein corresponding to the second group (ctrl background)

Value

A numeric vector of interaction stoichiometries