Compute correlation in protein recruitment from interaction stoichiometries computed across all conditions for each biological replicate. Pearson correlations are used.

compute_correlations(res, idx = NULL, log = FALSE, nmax = NULL,
  strict = TRUE, Rmin = 0)

Arguments

res

an InteRactome

idx

indexes of the set of proteins for which correlations will be computed

log

logical, use log-transformed stoichiometries

nmax

integer, limits the number of edges per node

strict

logical, if TRUE, ensures a strict upper bound on the maximal degree

Rmin

minimum absolute value of the Pearson R coefficient

Value

a data.frame with protein correlation information (correlation coefficient in column 'r_corr' and associated p-value in column 'p-corr')